Facilities

Phase 1 Capability

Phase 1 population
Adult solid tumour and haematology

Phase 1 Mechanisms
Gene therapy, Immunotherapy, small molecules

First-in-Man studies
Yes

Centre specific translational research interest
Gene and immunotherapy

Multi-centre Phase 1 studies
Yes

 

Technology/equipment available within the centre

  • Provision of GMP-quality cellular products
  • Clinical grade selection of T cell by HLA-peptide tetramers
  • Laser capture microdissection
  • Microarray analysis
  • Proteomics
  • NMR facilities for metabolomics
 

Other Facilities (e.g. Wellcome Trust CRF)

  • CTU; 6 exisiting research units
  • Cancer Research UK Institute for Cancer Studies (ICS)
  • Accredited Cancer Trials Unit by the National Cancer Research Institute
  • Cancer Research UK Key Centre for Early Phase Trials
  • Cancer Research UK Clinical Cancer Research Centre
  • Wellcome Trust Clinical Research Facility (WTCRF)
  • Centre for Clinical Haematology
  • Henry Wellcome Building for NMR Spectroscopy
 

Sample collection

Tissue Banking Activity
Local banks and National Trial tissue

Centre contact responsible for sample collection
Dr Jane Steele