
Cardiff
Horizontal Tabs
Treatment Modalities
Biologics
Radiotherapy
Immunotherapy
Surgery
Facilities/Translational Research
Phase 1 Capability
- Acute Myeloid Leukaemia
- First-in-Man studies
- Multi-centre Phase 1 studies
Centre specific translational research interest
- Mutation and gene array analysis
- New agent sensitivity screening (e.g. anti-cancer agents, Ret targeting)
- Biomarkers (e.g. IHC biomarker assay development (endocrine-resistant breast cancers))
Other Facilities
- Wales CTU
- Clinical Research Facility
Sample collection
- Tissue Banking Activity: Wales Cancer Bank: AML Cell Bank
- Centre contact responsible for sample collection: Cancer Bank (A Parry-Jones), AML (Dr Paul White).
ECMC funding provides infrastructure support for early phase and translational research. From the ECMC Cardiff portfolio, the following trials have been carried out.
Trial activity between 2012-2015:

Trial by disease type between 2012-2015:
Cardiff scientists developed an agent for hepatitis C...using the same approach, they have recently developed an anti-cancer agent which has entered phase 1/2 clinical trial in pancreatic cancer and other solid tumours