Manchester
Manchester ECMC aims to expand and develop its experimental cancer medicine portfolio in areas such as radiotherapy, proteomics, metabolomics and imaging. The Centre has an active early phase (phase I/II) clinical trial programme in various cancer types, with related biomarkers studies, which aim to inform treatment decisions and monitor the effectiveness of therapies.
Research Areas
Aims and Focus
- Increase the number and quality of early phase clinical trials
- Develop informative biomarkers (discovery, optimisation, validation, pharmacokinetics (PK) / pharmacodynamics (PD), biological effective dose)
- Develop and validate generic indicators of tumour apoptosis and anti-angiogenesis
- Develop clinical proteomics/metabolomics
- Conduct early phase Clinical Immunology trials and translational PD
- Develop, integrate and expand imaging methodologies in preclinical models and early clinical trials
- Increase capability to deliver targeted radiotherapies
- Develop radiogenomics and image guided radiotherapy
- Integrate GCLP compliant Laboratory QA systems into early clinical trials
Disease areas
Relevant to all types of cancer.
Goals
Skills

Manchester ECMC principal investigators and staff have a range of skills and expertise.
Facilities

Manchester ECMC has access to a range of research facilities that are utilised in studies.
Achievements

To learn more about the scientific and operational achievements of Manchester ECMC go to:
Centre Lead
Professor Malcolm Ranson
Derek Crowther Unit
Christie Hospital Foundation Trust
Wilmslow Road
MANCHESTER
M20 4BX
Tel 0161 446 3743
Fax 0161 446 8342
Administrative Support
Ms Aileen Jardine
Scientific Administrator
Clinical and Experimental Pharmacology
Paterson Institute for Cancer Research
Wilmslow Road
MANCHESTER
M20 4BX
Tel: +44 (0)161 446 3036
Fax: +44 (0)161 446 3109
Research Development Manager
Dr Kate Vaughan
University of Manchester
Wolfson Molecular Imaging Centre
Palatine Road
Manchester
M20 3LJ
Tel: +44 (0)161 446 3037
ECMC / CancerHelp UK Database Link
Matthew Richardson
Research Business Manager
The Christie NHS Foundation Trust
Wilmslow Road
Manchester M20 4BX
Direct Line: +44 (0) 161 446 8349
Mob: +44 (0) 7772 121 166
Clinical Trials Enquiries
You can also find out about trials recruiting in London on the CancerHelp UK clinical trials database.
