The Role of Advanced Nurse Practitioners in Early Phase Oncology Research

Advanced Nurse Practitioners (ANPs) play a vital role in early-phase oncology research across the UK, bridging the gap between clinical care and research delivery. Their extended scope of practice, including clinical assessment, prescribing, and decision-making, supports the wider research team in delivering more autonomous and patient-centred care within clinical trials. The integration of ANPs into research enhances patient access and experience while improving operational efficiency.

The specific responsibilities of ANPs can differ across sites, trials, and sponsors, but often include patient screening, consent discussions, and administration of investigational treatments. Thanks to their advanced clinical skills, ANPs are able to assess patients, manage toxicities, and adjust dosing in accordance with trial protocols. As independent prescribers, they can act swiftly to address side effects and assist patients with symptom management.

ANPs also contribute significantly to multidisciplinary team (MDT) meetings, offering clinical insights that enhance both the safety and feasibility of trials. Their role allows them to practise advanced clinical reasoning and make independent decisions, which helps to alleviate the workload of other clinicians and accelerates trial delivery.

The impact of ANPs on clinical trial sites is substantial. Their involvement enhances trial capacity, expedites patient recruitment, and provides timely clinical interventions. Importantly, patients benefit from holistic, expert support throughout their trial journey, resulting in improved care continuity and overall satisfaction.

Within the ECMC Network, we recognise the importance of embedding ANP roles into research teams and structuring our centres to make full use of the breadth of research nursing roles. This approach maximises capacity and places patients at the centre of our clinical research delivery.

We are pleased to note that the Nursing and Midwifery Council (NMC) is undertaking a review of ANP roles within the research setting. We support this work, which proposes the development of standards of proficiency and revalidation requirements tailored for ANPs working in research.

Hear from Linda Gomm, an Advanced Nurse Practitioner in the ECMC Network, on her experiences and perspectives in the evolving research landscape.