King’s Health Partners adult centre
This centre specialises in developing and delivering early‑phase trials for novel molecular and cellular cancer immunotherapies, building on discoveries from King’s College London laboratories.
Centre overview
Our King’s Health Partners adult experimental cancer medicine centre (ECMC) drives translation of first‑in‑class agents into the clinic, including IgE‑based antibodies and on‑site manufactured CAR‑T cell therapies for solid tumours, supporting both academic and industry‑partnered studies.
Since opening its first trial in 2007, this centre has rapidly expanded its early‑phase portfolio across thoracic, gastrointestinal, gynaecological and skin cancers.
Trials are delivered through the NIHR Clinical Research Facility at Guy’s Hospital. This is London’s only MHRA‑accredited NHS‑managed Clinical Research Facility and is supported by strong governance and surgical oncology expertise.
Expertise
molecular immunotherapy
cellular immunotherapy
advanced therapy manufacturing and vaccines
small molecules and RNA therapy
surgical diagnostics and biomarkers, including functional imaging
Key contacts
James Spicer - Centre co-lead
Professor Spicer is a Professor of Experimental Cancer Medicine at King’s College London, and Director of the NIHR Clinical Research Facility at Guy’s & St Thomas’ and is a medical oncologist and phase 1 trialist. He is a co-founder of two spin-out companies. He is an NIHR Senior Investigator.
Debashis Sarker - Centre co-lead
Debashis Sarker is Professor in Experimental Oncology at King’s College London and Consultant Medical Oncologist at Guy’s, St Thomas’ and King’s College Hospitals. Research focuses on first-in-human trials, immunotherapy and genomics, specialising in liver, pancreatic and neuroendocrine cancers. He holds leadership roles in Guy’s St Thomas’ NIHR Clinical Research Facility and NHS England genomics.
Ambi Williams - Centre business lead / Patient and public involvement lead
Ambi Williams is the Research Manager for King’s Health Partners and leads the South East London Consumer Research Panel, who support researchers with their studies, providing advice on patient information sheets, protocols and research proposals. Ambi also sits on the City of London Patient and Public Involvement Committee.
Contact details
Guy's Cancer Centre
Guys Hospital
Great Maze Pond
SE1 9RT
Programme office email:
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